In a mixing bowl, combine ground beef, salt, black pepper, garlic powder, onion powder, and Worcestershire sauce.

Mix gently until just combined; do not overwork the meat.

Divide the mixture into 4 equal portions and shape them into patties.

Preheat the grill or frying pan over medium-high heat.

Cook the patties for about 4-5 minutes on each side, or until they reach your desired doneness.

Let the patties rest for a few minutes before serving.